BPC-157 vs TB-500: BPC-157 is a 15-amino-acid fragment of a gastric juice protein, and TB-500 is a 7-amino-acid synthetic fragment of thymosin beta-4. This comparison covers how the two research peptides differ in sequence, molecular weight and published research, and where they appear together in CoreVionRX blends.
Quick answer: BPC-157 (Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val, 1419.5 g/mol) and TB-500 (Ac-LKKTETQ, 889.0 g/mol) are different synthetic peptides. Both are studied mostly in cell and animal models, and both are sold for laboratory research only; neither is an FDA-approved drug.
BPC-157 · 10mg vial
TB-500 research peptide
BPC-157 vs TB-500: Quick Comparison
What Is BPC-157?
BPC-157 (Body Protection Compound 157) is a synthetic 15-amino-acid research peptide taken from the sequence of a larger protein that Croatian researchers isolated from gastric juice in the early 1990s. Its developers describe it as stable in gastric juice, which is unusual for a peptide.
Published studies have examined it mostly in rodent and cell-culture models: tendon fibroblasts, blood-vessel formation (VEGFR2 signaling) and gastrointestinal models. Human data are very limited. The BPC-157 research peptide guide covers its molar mass, sequence, HPLC testing, lab prep and storage.
What Is TB-500?
TB-500 is a synthetic 7-amino-acid peptide, Ac-LKKTETQ, that matches the actin-binding region of thymosin beta-4, a 43-amino-acid protein found in most cells. Thymosin beta-4 binds G-actin, the single-unit form of the cell’s actin building block.
Research on TB-500 and thymosin beta-4 has looked at actin binding and cell migration, mostly in cell and animal models. See the TB-500 5mg product page for its specifications.
BPC-157 vs TB-500: Key Differences
The two peptides differ in size, origin and the pathways researchers have examined.
- Size: BPC-157 has 15 amino acids and weighs 1419.5 g/mol; TB-500 has 7 amino acids plus an acetyl group and weighs 889.0 g/mol.
- Origin: BPC-157 comes from a gastric juice protein; TB-500 comes from thymosin beta-4.
- Pathways studied: BPC-157 papers focus on growth-factor receptor signaling (VEGFR2) and FAK-paxillin signaling; TB-500 and thymosin beta-4 papers focus on actin binding and cell migration.
Why Are BPC-157 and TB-500 Studied Side by Side?
Researchers compare them because both are studied in tissue-repair models but through different pathways. That difference is also why the two appear together in multi-peptide research blends.
CoreVionRX supplies both individually and in three blends: Wolverine 20mg (BPC-157 10mg + TB-500 10mg), GLOW 70mg (GHK-Cu 50mg, BPC-157 10mg, TB-500 10mg) and KLOW 80mg (GLOW plus KPV 10mg).
Frequently Asked Questions
What is the difference between BPC-157 and TB-500?
BPC-157 is a 15-amino-acid fragment of a gastric juice protein (1419.5 g/mol). TB-500 is a 7-amino-acid fragment of thymosin beta-4, Ac-LKKTETQ (889.0 g/mol). Researchers have studied them through different pathways: growth-factor receptor signaling for BPC-157, actin binding and cell migration for TB-500.
What is the difference between TB-500 and thymosin beta-4?
Thymosin beta-4 is the natural 43-amino-acid protein. TB-500 is a short synthetic peptide, Ac-LKKTETQ, that matches its actin-binding region.
Which CoreVionRX products contain both BPC-157 and TB-500?
Wolverine 20mg (BPC-157 10mg and TB-500 10mg), GLOW 70mg (GHK-Cu 50mg, BPC-157 10mg, TB-500 10mg) and KLOW 80mg (the GLOW components plus KPV 10mg).
Where can I buy BPC-157 and TB-500 for research?
CoreVionRX carries BPC-157 10mg and TB-500 5mg individually, each HPLC and mass-spec verified, and both in the Wolverine, GLOW and KLOW blends. All products are for laboratory research use only.
Related research guides: BPC-157 research peptide guide → · KLOW 80mg research guide → · How to reconstitute research peptides →
Research availability: BPC-157 10mg and TB-500 5mg are available from CoreVionRX with independent HPLC purity and mass-spec identity testing. For laboratory research use only.
The Bottom Line
BPC-157 and TB-500 are different peptides with different sequences, weights and research histories, so check which one a study used before comparing findings. Use the reconstitution calculator for prep, and browse the research catalog for both compounds. For laboratory research use only.
