TB-500 — synthetic fragment of Thymosin Beta-4. A 43-amino-acid peptide studied for actin-binding properties, soft tissue repair, and angiogenesis in preclinical models. 10mg lyophilized, HPLC + mass spec verified.
TB-500 is a synthetic analog of Thymosin Beta-4 (Tβ4), a naturally occurring 43-amino-acid protein found in virtually all nucleated cells. The research peptide marketed as TB-500 is typically a synthetic fragment corresponding to the actin-binding domain of Tβ4, responsible for the protein’s observed effects in preclinical healing models.
In preclinical research, TB-500 is studied for its role in actin regulation, angiogenesis, and soft tissue repair. Researchers have investigated its effects on wound closure, muscle fiber regeneration, and cardiac recovery in rodent models.
For a full breakdown of the research literature, read our TB-500 research guide →
CoreVionRX doesn’t manufacture peptides. What we do — rigorously — is verify every batch before it reaches our catalog.
Everything you need to evaluate this compound for your research protocol.
| Specification | Value |
|---|---|
| Compound | TB-500 (Thymosin Beta-4 Fragment) |
| Origin | Synthetic analog of Thymosin Beta-4 actin-binding domain |
| Amino Acids | 43 (full fragment) |
| CAS Number | 77591-33-4 |
| Form | Lyophilized powder |
| Vial Size | 10mg per vial |
| Purity | ≥98% by reversed-phase HPLC |
| Identity | Confirmed by electrospray ionization mass spectrometry |
| Storage (lyophilized) | −20°C, protected from light and moisture. Stable 24+ months. |
| Reconstitution | Bacteriostatic water — typical 1–5mg/mL |
| Documentation | Lot-specific COA with HPLC chromatogram — included with every order |
All published research is preclinical — cell cultures and animal models. No human clinical trial data exists for TB-500. Here’s where the science currently stands.
Goldstein AL. et al. (2005) Expert Opin Biol Ther 5(1):37-43
Smart N. et al. (2007) Nature 445(7128):177-82
Bock-Marquette I. et al. (2004) Nature 432(7016):466-72
Most peptide vendors claim purity. We document it. Every compound ships with independent lab verification — not because regulations require it, but because you deserve to know exactly what you’re working with.
In stock. COA included. HPLC + mass spec verified. Ships with full documentation.
For laboratory research use only. Not for human or animal consumption.
CoreVionRX supplies research compounds to qualified laboratories and research institutions.
Documentation & Testing Standards
Every batch is independently tested before release. Research peptide FAQs · CoreVionRX testing standards
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