Research Compound · GHK-Cu

GHK-Cu Research Peptide —
Independently Verified.

GHK-Cu — copper-binding tripeptide (Gly-His-Lys) complexed with copper. One of the most widely studied copper peptides for collagen synthesis, wound healing, and antioxidant pathway research. 100mg lyophilized, HPLC + mass spec verified.

≥98% HPLC PurityCopper Content VerifiedLyophilized · 100mgCOA IncludedUSA Operations

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$65.00

per 100mg vial

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COA included with every order
For laboratory research use only

HPLC Verified≥98% purity confirmed per lot

COA IncludedLot-specific certificate ships with order

Mass Spec IDMolecular identity confirmed per batch

USA OperationsVerified sourcing. Documented chain.

About This Compound

What Is GHK-Cu?

GHK-Cu is a naturally occurring tripeptide-copper complex consisting of glycine, histidine, and lysine bound to a copper(II) ion. It was first isolated from human plasma in 1973 by Loren Pickart and is found in plasma, saliva, and urine. GHK levels decline significantly with age, making it a subject of interest in aging and regenerative research.

In preclinical research, GHK-Cu is studied for its role in collagen and elastin synthesis, wound healing, angiogenesis, antioxidant enzyme upregulation, and gene expression modulation. Over 3,000 human genes are reported to be affected by GHK-Cu in laboratory studies.

For a full breakdown of the research literature, read our GHK-Cu research guide →

// compound profile

CompoundGHK-Cu Tripeptide

SequenceGly-His-Lys·Cu(II)

Amino Acids3 (tripeptide)

Copper Content14-16% by weight

FormLyophilized powder

Size100mg per vial

Purity≥98% HPLC

What Sets Us Apart

We Verify Before We Ship.

CoreVionRX doesn’t manufacture peptides. What we do — rigorously — is verify every batch before it reaches our catalog.

≥98%

Purity by Reversed-Phase HPLC

HPLC separates the compound from any impurities and measures the exact purity percentage. The chromatogram is documented on your COA.

MS/MS

Mass Spectrometry Identity Check

Electrospray ionization mass spectrometry verifies the molecular weight matches the compound specification. Confirms you’re getting the actual compound.

Lot #

Lot-Specific Certificate of Analysis

Your COA is tied to your specific production lot — not a generic document. This is not standard practice in this market. We made it one anyway.

100%

Documented Before Listing

No compound reaches our catalog without clearing our verification process first. If documentation isn’t available for a batch, that batch doesn’t ship.

Technical Specifications

Full Product Data

Everything you need to evaluate this compound for your research protocol.

Specification	Value
Compound	GHK-Cu (Glycyl-L-histidyl-L-lysine·copper complex)
Sequence	Gly-His-Lys complexed with Cu(II)
Amino Acids	3 (tripeptide)
Copper Content	14-16% by weight (verified)
Form	Lyophilized powder (blue coloration from copper)
Vial Size	100mg per vial
Purity	≥98% by reversed-phase HPLC
Identity	Confirmed by mass spectrometry with copper content verification
Storage (lyophilized)	−20°C, protected from light and moisture. Stable 24+ months.
Reconstitution	Bacteriostatic water or sterile water
Documentation	Lot-specific COA with HPLC chromatogram and copper content — included with every order

Preclinical Research

What Researchers Study GHK-Cu For

All published research is preclinical — cell cultures and animal models. No human clinical trial data exists for GHK-Cu. Here’s where the science currently stands.

Wound Healing & Collagen Research

GHK-Cu is extensively studied for its stimulatory effects on collagen and elastin synthesis in fibroblast cultures and wound healing models. Research examines accelerated wound closure, tensile strength recovery, and extracellular matrix remodeling.

Pickart L. & Margolina A. (2018) Biomolecules 8(3):55

Antioxidant Pathway Studies

Preclinical research investigates GHK-Cu’s upregulation of superoxide dismutase and catalase — key antioxidant enzymes. Studies examine how copper complexation enables GHK-Cu to modulate oxidative stress in cell culture models.

Buffoni F. et al. (1999) Arch Biochem Biophys 367(2):205-13

Gene Expression Modulation

GHK-Cu is studied as a gene expression modulator. Microarray studies have reported that GHK-Cu affects expression of over 3,000 human genes — including genes related to inflammation resolution, tissue remodeling, and nervous system function.

Pickart L. et al. (2012) J Aging Res 2012:324279

Why CoreVionRX

Documentation Is the Product.

Most peptide vendors claim purity. We document it. Every compound ships with independent lab verification — not because regulations require it, but because you deserve to know exactly what you’re working with.

Independent HPLC Testing

Every batch runs through reversed-phase HPLC before we list it. The chromatogram appears on your COA. Verify the peak profile yourself.

Lot-Specific Documentation

Your COA is tied to your production lot — not a template document. “COA available upon request” is not how we operate.

Transparent About What We Are

We source and verify. We are not a synthesis lab. That honesty is deliberate — it’s the only way to build a brand worth buying from twice.

Lyophilized for Stability

Ships as lyophilized powder — stable at −20°C for 24+ months. Full integrity maintained until you’re ready to reconstitute.

Common Questions

Straight Answers.

What is GHK-Cu and where does it naturally occur?

GHK-Cu is a naturally occurring tripeptide-copper complex (Gly-His-Lys·Cu²⁺) found in human plasma, saliva, and urine. First isolated in 1973, its plasma concentration declines with age. The research peptide is a synthetic version of this naturally occurring compound.

What research areas use GHK-Cu?

GHK-Cu is studied for collagen and elastin synthesis in fibroblasts, wound healing and tissue remodeling, antioxidant enzyme upregulation, angiogenesis, and broad gene expression modulation. All published research is preclinical.

Why does the GHK-Cu powder appear blue?

The blue coloration is from the copper(II) ion complexed to the tripeptide — this is expected and indicates proper copper coordination. Your COA will document the copper content (typically 14-16% by weight) to verify the complex is correctly formed.

How do I reconstitute GHK-Cu?

Reconstitute with bacteriostatic water or sterile water. GHK-Cu dissolves readily due to its small size and ionic character. The solution will appear light blue. Typical research concentrations: 1–10mg/mL. Use our reconstitution calculator for exact volumes.

How should GHK-Cu be stored?

Store lyophilized at −20°C, protected from light and moisture. Stable for 24+ months. After reconstitution, store at 2–8°C. Avoid excessive light exposure of the reconstituted solution as copper complexes can be photosensitive.

Continue Your Research

Related Resources

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≥98% HPLC PurityLot-Specific COAMass Spec VerifiedUSA Operations

For laboratory research use only. Not for human or animal consumption.
CoreVionRX supplies research compounds to qualified laboratories and research institutions.

GHK-Cu Research Peptide —Independently Verified.