This CJC-1295 DAC research peptide guide covers purity verification, quality standards, and handling for the long-acting GHRH analog.
Research Compound · CJC-1295 DAC
CJC-1295 DAC Research Peptide — Independently Verified.
CJC-1295 with DAC — tetrasubstituted 30-amino-acid GHRH analog with Drug Affinity Complex for extended half-life. Studied for GH secretion and pituitary research. 5mg lyophilized, HPLC + mass spec verified.
COA included with every order For laboratory research use only
HPLC Verified≥98% purity confirmed per lot
COA IncludedLot-specific certificate ships with order
Mass Spec IDMolecular identity confirmed per batch
USA OperationsVerified sourcing. Documented chain.
About This Compound
What Is CJC-1295 DAC?
CJC-1295 with DAC is a synthetic analog of growth hormone-releasing hormone (GHRH) — a 30-amino-acid peptide with four amino acid substitutions that improve metabolic stability. The “DAC” refers to its Drug Affinity Complex: a lysine-maleimide conjugate that enables the peptide to bind albumin in plasma, dramatically extending its half-life from minutes to several days.
In preclinical research, CJC-1295 with DAC is studied for its ability to stimulate growth hormone secretion from pituitary somatotrophs, GH pulse research, and IGF-1 modulation in animal models. The DAC modification makes it a useful tool for studying sustained GH elevation compared to native GHRH.
CoreVionRX doesn’t manufacture peptides. What we do — rigorously — is verify every batch before it reaches our catalog.
≥98%
Purity by Reversed-Phase HPLC
HPLC separates the compound from any impurities and measures the exact purity percentage. The chromatogram is documented on your COA — not a number we made up.
MS/MS
Mass Spectrometry Identity Check
Electrospray ionization mass spectrometry verifies the molecular weight matches the compound specification. This confirms you’re getting the actual compound — not a substitute or mis-labeled batch.
Lot #
Lot-Specific Certificate of Analysis
Your COA is tied to your specific production lot — not a generic document. This is not standard practice in this market. We made it one anyway.
100%
Documented Before Listing
No compound reaches our catalog without clearing our verification process first. If documentation isn’t available for a batch, that batch doesn’t ship.
Technical Specifications
Full Product Data
Everything you need to evaluate this compound for your research protocol.
Specification
Value
Compound
CJC-1295 with DAC (Drug Affinity Complex)
Class
Tetrasubstituted GHRH analog
Amino Acids
30 (with maleimide-lysine DAC modification)
Mechanism
Albumin binding via DAC for extended plasma half-life
Form
Lyophilized powder
Vial Size
5mg per vial
Purity
≥98% by reversed-phase HPLC
Identity
Confirmed by electrospray ionization mass spectrometry (including DAC moiety)
Storage (lyophilized)
−20°C, protected from light and moisture. Stable 24+ months.
Storage (reconstituted)
2–8°C. Use within protocol timeframe.
Reconstitution
Bacteriostatic water
Documentation
Lot-specific COA with HPLC chromatogram — included with every order
Preclinical Research
What Researchers Study CJC-1295 DAC For
All published research is preclinical — cell cultures and animal models. No human clinical trial data exists for CJC-1295 DAC. Here’s where the science currently stands.
GHRH Analog Research
CJC-1295 is studied as a GHRH receptor agonist, investigating its ability to stimulate GH secretion from pituitary somatotrophs. The four amino acid substitutions confer metabolic stability compared to native GHRH(1-29).
Jetté L. et al. (2005) Endocrinology 146(7):3052-8
Extended Half-Life Studies
The DAC modification is central to CJC-1295 research. Studies examine how albumin binding via the maleimide-lysine conjugate extends the peptide’s plasma half-life from minutes to days, enabling prolonged GH secretion paradigms.
CJC-1295 with DAC is used as a pharmacological tool to study pituitary somatotroph function and downstream IGF-1 production in animal models, investigating the GH/IGF-1 axis and its metabolic effects.
Semenistaya EN. et al. (2016) Drug Test Anal 8(7):659-66
Why CoreVionRX
Documentation Is the Product.
Most peptide vendors claim purity. We document it. Every compound ships with independent lab verification — not because regulations require it, but because you deserve to know exactly what you’re working with.
Independent HPLC Testing
Every batch runs through reversed-phase HPLC before we list it. The chromatogram appears on your COA. Verify the peak profile yourself.
Lot-Specific Documentation
Your COA is tied to your production lot — not a template document used across all orders. “COA available upon request” is not how we operate.
Transparent About What We Are
We source and verify. We are not a synthesis lab. That honesty is deliberate — it’s the only way to build a brand worth buying from twice.
Lyophilized for Stability
Ships as lyophilized powder — stable at −20°C for 24+ months. Full integrity maintained until you’re ready to reconstitute.
Common Questions
Straight Answers.
What is CJC-1295 with DAC and how does the DAC work?
CJC-1295 with DAC is a 30-amino-acid GHRH analog with four amino acid substitutions plus a Drug Affinity Complex (DAC) modification — a lysine-maleimide group that covalently binds albumin in the bloodstream. This albumin binding dramatically extends the peptide’s plasma half-life from minutes (native GHRH) to several days.
What research areas use CJC-1295 with DAC?
Research focuses on GHRH receptor pharmacology, extended GH secretion paradigms, pituitary somatotroph stimulation, and IGF-1 axis modulation in rodent models. All research is preclinical.
What is the difference between CJC-1295 with DAC and without DAC?
CJC-1295 without DAC (also called Modified GRF 1-29) is the base GHRH analog without the albumin-binding modification — it has a half-life of 30–45 minutes. CJC-1295 with DAC includes the DAC modification extending half-life to several days. The two are used in different research paradigms depending on whether prolonged GH elevation is studied.
Is CJC-1295 DAC often researched with Ipamorelin?
Yes. CJC-1295 with DAC and Ipamorelin are commonly combined in research protocols. CJC-1295 acts on the GHRH receptor while Ipamorelin acts on GHS-R1a — two complementary GH-stimulating pathways studied together for synergistic GH release.
How should CJC-1295 DAC be stored?
Store lyophilized at −20°C, protected from light and moisture. Stable for 24+ months. After reconstitution, store at 2–8°C. The DAC modification does not affect standard lyophilized storage requirements.
For laboratory research use only. Not for human or animal consumption. CoreVionRX supplies research compounds to qualified laboratories and research institutions.
CJC-1295 DAC Research Peptide: What to Know Before You Buy
cjc-1295 dac research peptide from CoreVionRX is verified at ≥99%% HPLC purity with mass spectrometry confirming the exact peptide sequence.
Every cjc-1295 dac research peptide vial ships with HPLC verification and a lot-specific COA.
Every vial of cjc-1295 dac research peptide ships with a lot-specific certificate of analysis so you can verify exactly what is in the vial you received.
CoreVionRX cjc-1295 dac research peptide is verified by independent third-party testing — mass spectrometry confirms sequence identity and HPLC confirms purity.
Store cjc-1295 dac research peptide as a lyophilized powder in cool, dark conditions; once reconstituted, keep refrigerated and use within your protocol window.
For accurate reconstitution of cjc-1295 dac research peptide, use the peptide calculator to calculate the exact water volume needed.
Researchers working with cjc-1295 dac research peptide should confirm ≥99%% HPLC purity and a lot-specific COA with every order.
For reconstitution, add bacteriostatic water slowly and store cjc-1295 dac research peptide refrigerated after mixing. Use the peptide calculator to get concentration right.
When sourcing cjc-1295 dac research peptide, the most important check is purity: every CoreVionRX vial is verified at ≥99% HPLC with a lot-specific COA.
Peer-reviewed research on cjc-1295 dac research peptide is indexed at PubMed. For research use only.
All CoreVionRX research peptides ship with a lot-specific COA, ≥99%% HPLC purity, and mass-spec identity confirmation. Use our reconstitution calculator for prep. For research use only.
Sourcing verified cjc-1295 dac research peptide is the first step in any reliable research protocol.
