Research Compound · CJC-1295 DAC

CJC-1295 DAC Research Peptide —
Independently Verified.

CJC-1295 with DAC — tetrasubstituted 30-amino-acid GHRH analog with Drug Affinity Complex for extended half-life. Studied for GH secretion and pituitary research. 5mg lyophilized, HPLC + mass spec verified.

≥98% HPLC PurityMass Spec VerifiedLyophilized · 5mgCOA IncludedUSA Operations

Order CJC-1295 DAC — $65.00 Read the research guide

$65.00

per 5mg vial

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COA included with every order
For laboratory research use only

HPLC Verified≥98% purity confirmed per lot

COA IncludedLot-specific certificate ships with order

Mass Spec IDMolecular identity confirmed per batch

USA OperationsVerified sourcing. Documented chain.

About This Compound

What Is CJC-1295 DAC?

CJC-1295 with DAC is a synthetic analog of growth hormone-releasing hormone (GHRH) — a 30-amino-acid peptide with four amino acid substitutions that improve metabolic stability. The “DAC” refers to its Drug Affinity Complex: a lysine-maleimide conjugate that enables the peptide to bind albumin in plasma, dramatically extending its half-life from minutes to several days.

In preclinical research, CJC-1295 with DAC is studied for its ability to stimulate growth hormone secretion from pituitary somatotrophs, GH pulse research, and IGF-1 modulation in animal models. The DAC modification makes it a useful tool for studying sustained GH elevation compared to native GHRH.

For a full breakdown of the research literature, read our CJC-1295 DAC research guide →

// compound profile

CompoundCJC-1295 with DAC

ClassGHRH analog with Drug Affinity Complex

Amino Acids30 (tetrasubstituted)

FormLyophilized powder

Size5mg per vial

Purity≥98% HPLC

Storage−20°C / 24+ months

What Sets Us Apart

We Verify Before We Ship.

CoreVionRX doesn’t manufacture peptides. What we do — rigorously — is verify every batch before it reaches our catalog.

≥98%

Purity by Reversed-Phase HPLC

HPLC separates the compound from any impurities and measures the exact purity percentage. The chromatogram is documented on your COA — not a number we made up.

MS/MS

Mass Spectrometry Identity Check

Electrospray ionization mass spectrometry verifies the molecular weight matches the compound specification. This confirms you’re getting the actual compound — not a substitute or mis-labeled batch.

Lot #

Lot-Specific Certificate of Analysis

Your COA is tied to your specific production lot — not a generic document. This is not standard practice in this market. We made it one anyway.

100%

Documented Before Listing

No compound reaches our catalog without clearing our verification process first. If documentation isn’t available for a batch, that batch doesn’t ship.

Technical Specifications

Full Product Data

Everything you need to evaluate this compound for your research protocol.

Specification	Value
Compound	CJC-1295 with DAC (Drug Affinity Complex)
Class	Tetrasubstituted GHRH analog
Amino Acids	30 (with maleimide-lysine DAC modification)
Mechanism	Albumin binding via DAC for extended plasma half-life
Form	Lyophilized powder
Vial Size	5mg per vial
Purity	≥98% by reversed-phase HPLC
Identity	Confirmed by electrospray ionization mass spectrometry (including DAC moiety)
Storage (lyophilized)	−20°C, protected from light and moisture. Stable 24+ months.
Storage (reconstituted)	2–8°C. Use within protocol timeframe.
Reconstitution	Bacteriostatic water
Documentation	Lot-specific COA with HPLC chromatogram — included with every order

Preclinical Research

What Researchers Study CJC-1295 DAC For

All published research is preclinical — cell cultures and animal models. No human clinical trial data exists for CJC-1295 DAC. Here’s where the science currently stands.

GHRH Analog Research

CJC-1295 is studied as a GHRH receptor agonist, investigating its ability to stimulate GH secretion from pituitary somatotrophs. The four amino acid substitutions confer metabolic stability compared to native GHRH(1-29).

Jetté L. et al. (2005) Endocrinology 146(7):3052-8

Extended Half-Life Studies

The DAC modification is central to CJC-1295 research. Studies examine how albumin binding via the maleimide-lysine conjugate extends the peptide’s plasma half-life from minutes to days, enabling prolonged GH secretion paradigms.

Ionescu M. & Frohman LA. (2006) J Clin Endocrinol Metab 91(3):799-805

Pituitary & IGF-1 Research

CJC-1295 with DAC is used as a pharmacological tool to study pituitary somatotroph function and downstream IGF-1 production in animal models, investigating the GH/IGF-1 axis and its metabolic effects.

Semenistaya EN. et al. (2016) Drug Test Anal 8(7):659-66

Why CoreVionRX

Documentation Is the Product.

Most peptide vendors claim purity. We document it. Every compound ships with independent lab verification — not because regulations require it, but because you deserve to know exactly what you’re working with.

Independent HPLC Testing

Every batch runs through reversed-phase HPLC before we list it. The chromatogram appears on your COA. Verify the peak profile yourself.

Lot-Specific Documentation

Your COA is tied to your production lot — not a template document used across all orders. “COA available upon request” is not how we operate.

Transparent About What We Are

We source and verify. We are not a synthesis lab. That honesty is deliberate — it’s the only way to build a brand worth buying from twice.

Lyophilized for Stability

Ships as lyophilized powder — stable at −20°C for 24+ months. Full integrity maintained until you’re ready to reconstitute.

Common Questions

Straight Answers.

What is CJC-1295 with DAC and how does the DAC work?

CJC-1295 with DAC is a 30-amino-acid GHRH analog with four amino acid substitutions plus a Drug Affinity Complex (DAC) modification — a lysine-maleimide group that covalently binds albumin in the bloodstream. This albumin binding dramatically extends the peptide’s plasma half-life from minutes (native GHRH) to several days.

What research areas use CJC-1295 with DAC?

Research focuses on GHRH receptor pharmacology, extended GH secretion paradigms, pituitary somatotroph stimulation, and IGF-1 axis modulation in rodent models. All research is preclinical.

What is the difference between CJC-1295 with DAC and without DAC?

CJC-1295 without DAC (also called Modified GRF 1-29) is the base GHRH analog without the albumin-binding modification — it has a half-life of 30–45 minutes. CJC-1295 with DAC includes the DAC modification extending half-life to several days. The two are used in different research paradigms depending on whether prolonged GH elevation is studied.

Is CJC-1295 DAC often researched with Ipamorelin?

Yes. CJC-1295 with DAC and Ipamorelin are commonly combined in research protocols. CJC-1295 acts on the GHRH receptor while Ipamorelin acts on GHS-R1a — two complementary GH-stimulating pathways studied together for synergistic GH release.

How should CJC-1295 DAC be stored?

Store lyophilized at −20°C, protected from light and moisture. Stable for 24+ months. After reconstitution, store at 2–8°C. The DAC modification does not affect standard lyophilized storage requirements.

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Related Resources

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≥98% HPLC PurityLot-Specific COAMass Spec VerifiedUSA Operations

For laboratory research use only. Not for human or animal consumption.
CoreVionRX supplies research compounds to qualified laboratories and research institutions.

CJC-1295 DAC Research Peptide —Independently Verified.