Cognitive & Neuroprotection Peptides for Laboratory Research
Cognitive and neuroprotection peptides are studied for their roles in neuronal signaling, nerve growth factor (NGF) modulation, BDNF expression, and neuroprotective mechanisms. CoreVionRX supplies Semax, NAD+, and the CJC-1295 + Ipamorelin blend in this research category.
Peptides in This Research Category
Semax (ACTH(4-7)-Pro-Gly-Pro)
Semax is a heptapeptide analogue of ACTH(4-10) — specifically the sequence Met-Glu-His-Phe-Pro-Gly-Pro. Research has investigated its effects on BDNF expression, NGF production, and dopaminergic and serotonergic system modulation. It is among the most studied nootropic peptides in Russian neuropeptide research. View Semax research peptide →
NAD+ (Nicotinamide Adenine Dinucleotide)
NAD+ is a coenzyme central to cellular energy metabolism and a key substrate for sirtuins and PARPs. Research on NAD+ focuses on mitochondrial function, DNA repair mechanisms, and neuronal energy availability. It is not a peptide but is frequently co-studied with neuropeptides in cellular aging and neurodegeneration models. View NAD+ research →
CJC-1295 + Ipamorelin Blend
CJC-1295 is a growth hormone-releasing hormone (GHRH) analogue; Ipamorelin is a selective growth hormone secretagogue (GHS). Together they study pituitary GH axis stimulation from both receptor pathways simultaneously. Research on this combination includes neurological recovery models and sleep architecture studies. View CJC-1295 + Ipamorelin blend →
Research Applications
- BDNF and NGF expression studies
- Neuroprotection and neuronal survival models
- Sirtuin activation and NAD+ metabolism
- Growth hormone axis modulation research
- Dopaminergic and serotonergic signaling models
- Mitochondrial function in neural tissue
Frequently Asked Questions
What is Semax and how does it relate to ACTH?
Semax is a synthetic analogue of the ACTH(4-10) fragment — specifically shortened to the core sequence MEHFPGP (Met-Glu-His-Phe-Pro-Gly-Pro). Unlike ACTH itself, Semax lacks adrenocortical activity. Research interest focuses on its BDNF-stimulating and neuroprotective properties independent of cortisol pathways.
Why is NAD+ included in neuroprotection research?
NAD+ is a rate-limiting substrate for PARP (poly ADP-ribose polymerase) and sirtuin enzymes, both of which are central to DNA damage repair and cellular stress responses in neurons. Declining NAD+ levels are implicated in neurodegenerative research models. Laboratory studies often measure NAD+ alongside SIRT1 and SIRT3 expression.
What is the difference between CJC-1295 and Ipamorelin?
CJC-1295 acts on GHRH receptors in the pituitary, stimulating GH release through the GHRH pathway. Ipamorelin acts on ghrelin/GHS receptors (specifically GHSR), stimulating GH through a separate pathway. Using both in research provides dual-pathway stimulation of the GH axis, which is why they are frequently co-studied.
Compare CJC-1295 vs Ipamorelin → | Browse all research peptides →