Research Compound · NAD+

NAD+ Coenzyme Research —
Independently Verified.

NAD+ (Nicotinamide Adenine Dinucleotide) — essential coenzyme involved in cellular energy metabolism, sirtuin activation, and DNA repair. Not a peptide. 500mg dry powder, ≥98% by UV spectrophotometry.

≥98% UV SpectrophotometryHPLC VerifiedDry Powder · 500mgCOA IncludedUSA Operations

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Mass Spec IDIdentity confirmed per batch

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About This Compound

What Is NAD+?

NAD+ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme found in all living cells. It exists in two forms — oxidized (NAD+) and reduced (NADH) — and plays a central role in redox reactions that power cellular metabolism. NAD+ is not a peptide; it is a dinucleotide derived from niacin (Vitamin B3).

In research settings, NAD+ is studied for its role in sirtuin (SIRT1-7) activation, mitochondrial biogenesis, DNA repair via PARP enzymes, and age-related metabolic decline. Cellular NAD+ levels decline significantly with age, making it a central subject in longevity and metabolism research.

Read our NAD+ research guide →

// compound profile

CompoundNAD+

Full nameNicotinamide Adenine Dinucleotide

TypeCoenzyme (not a peptide)

FormDry powder (non-lyophilized)

Size500mg

Purity≥98% UV spectrophotometry

Storage−20°C sealed

Quality Standard

We Verify Before We Ship.

CoreVionRX doesn’t manufacture compounds. We verify every batch rigorously before it reaches our catalog.

≥98%

Purity by HPLC

Reversed-phase HPLC separates and measures compound purity. Documented on your lot-specific COA.

MS/MS

Mass Spec Identity

Molecular weight verified by ESI mass spectrometry — confirms you’re getting exactly what you ordered.

Lot #

Lot-Specific COA

Your COA tied to your production lot. Not standard in this market. We made it standard anyway.

100%

Pre-Listing Verification

No compound ships without full documentation cleared. Non-negotiable policy.

Technical Specifications

Full Product Data

Specification	Value
Compound	NAD+ (Nicotinamide Adenine Dinucleotide)
Type	Coenzyme — not a peptide or amino acid polymer
Form	Dry powder (non-lyophilized)
Vial Size	500mg
Purity	≥98% by UV spectrophotometry
Identity	Confirmed by HPLC and spectroscopic analysis
Storage	−20°C, sealed container, away from moisture and light
Solubility	Water-soluble — dissolves readily in aqueous buffer or sterile water
Documentation	Lot-specific COA with purity data — included with every order

Preclinical Research

What Researchers Study NAD+ For

All published research is preclinical — cell cultures and animal models.

Sirtuin Activation Research

NAD+ is the required co-substrate for sirtuin (SIRT1-7) deacylase enzymes. Research examines how NAD+ availability modulates sirtuin activity, downstream effects on gene expression, and implications for cellular aging models.

Guarente L. (2013) Cell 155(6):1241-2

Mitochondrial Biogenesis

NAD+-dependent pathways including SIRT1-PGC1α signaling are studied for their role in mitochondrial biogenesis and oxidative phosphorylation regulation. Research investigates how NAD+ supplementation affects mitochondrial density in muscle cell models.

Cantó C. et al. (2012) Cell Metab 15(6):838-47

DNA Repair Research

NAD+ is required for PARP (poly ADP-ribose polymerase) enzyme activity — a key mediator of DNA damage repair. Research examines how NAD+ availability affects PARP-mediated repair efficiency and genome stability in cell culture models.

Canto C. et al. (2015) Cell Metab 22(1):31-53

Why CoreVionRX

Documentation Is the Product.

Most vendors claim purity. We document it. Every compound ships with independent lab verification.

Independent HPLC Testing

Every batch through reversed-phase HPLC before listing. Chromatogram on your COA.

Lot-Specific COA

Your COA tied to your production lot — not a generic template.

Transparent Sourcing

We source and verify. Not a synthesis lab. That honesty builds the brand.

Stability Guaranteed

Lyophilized powder — stable at −20°C for 24+ months.

Common Questions

Straight Answers.

What is NAD+ and is it a peptide?

NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme — not a peptide. It is a dinucleotide derived from niacin (Vitamin B3) and is found in all living cells. CoreVionRX carries it as a research compound alongside its peptide catalog because it is frequently studied in longevity and metabolism research.

What research areas use NAD+?

NAD+ research focuses on sirtuin (SIRT1-7) activation, mitochondrial biogenesis via SIRT1-PGC1α pathways, DNA repair through PARP enzymes, and age-related metabolic decline. All research is preclinical or early-stage.

How does NAD+ differ from NMN or NR?

NAD+, NMN (Nicotinamide Mononucleotide), and NR (Nicotinamide Riboside) are related but distinct compounds. NMN and NR are NAD+ precursors — the body converts them to NAD+ intracellularly. Researchers choose between direct NAD+ and precursors based on their specific study design.

How do I dissolve NAD+ for research?

NAD+ is water-soluble and dissolves readily in sterile water, PBS, or appropriate aqueous buffer. No bacteriostatic water needed. Dissolve to your target concentration, filter-sterilize if required by protocol. NAD+ solutions are best used fresh.

How should NAD+ be stored?

Store dry powder at −20°C in a sealed container, away from moisture and light. NAD+ is hygroscopic — moisture accelerates degradation. Keep sealed until use. Solutions should be prepared fresh and not stored long-term.

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≥98% HPLCLot-Specific COAMass Spec VerifiedUSA Operations

For laboratory research use only. Not for human or animal consumption.

NAD+ Coenzyme Research —Independently Verified.