This NAD plus research compound guide covers purity verification, quality standards, and handling for cellular metabolism research.
NAD+ is a coenzyme found in every living cell. It acts as the fuel for cellular energy production and DNA repair. As we age, NAD+ levels naturally decline. Researchers are studying whether replenishing NAD+ through supplementation can support cellular function, longevity, and metabolic health.
Research Compound · NAD+
NAD+ Coenzyme Research — Independently Verified.
NAD+ (Nicotinamide Adenine Dinucleotide) — essential coenzyme involved in cellular energy metabolism, sirtuin activation, and DNA repair. Not a peptide. 500mg dry powder, ≥98% by UV spectrophotometry.
COA included with every order For laboratory research use only
HPLC Verified≥98% purity confirmed per lot
COA IncludedLot-specific certificate
Mass Spec IDIdentity confirmed per batch
USA OperationsVerified. Documented.
About This Compound
What Is NAD+?
NAD+ (Nicotinamide Adenine Dinucleotide) is an essential coenzyme found in all living cells. It exists in two forms — oxidized (NAD+) and reduced (NADH) — and plays a central role in redox reactions that power cellular metabolism. NAD+ is not a peptide; it is a dinucleotide derived from niacin (Vitamin B3).
In research settings, NAD+ is studied for its role in sirtuin (SIRT1-7) activation, mitochondrial biogenesis, DNA repair via PARP enzymes, and age-related metabolic decline. Cellular NAD+ levels decline significantly with age, making it a central subject in longevity and metabolism research.
CoreVionRX doesn’t manufacture compounds. We verify every batch rigorously before it reaches our catalog.
≥98%
Purity by HPLC
Reversed-phase HPLC separates and measures compound purity. Documented on your lot-specific COA.
MS/MS
Mass Spec Identity
Molecular weight verified by ESI mass spectrometry — confirms you’re getting exactly what you ordered.
Lot #
Lot-Specific COA
Your COA tied to your production lot. Not standard in this market. We made it standard anyway.
100%
Pre-Listing Verification
No compound ships without full documentation cleared. Non-negotiable policy.
Technical Specifications
Full Product Data
Specification
Value
Compound
NAD+ (Nicotinamide Adenine Dinucleotide)
Type
Coenzyme — not a peptide or amino acid polymer
Form
Dry powder (non-lyophilized)
Vial Size
500mg
Purity
≥98% by UV spectrophotometry
Identity
Confirmed by HPLC and spectroscopic analysis
Storage
−20°C, sealed container, away from moisture and light
Solubility
Water-soluble — dissolves readily in aqueous buffer or sterile water
Documentation
Lot-specific COA with purity data — included with every order
Preclinical Research
What Researchers Study NAD+ For
All published research is preclinical — cell cultures and animal models.
Sirtuin Activation Research
NAD+ is the required co-substrate for sirtuin (SIRT1-7) deacylase enzymes. Research examines how NAD+ availability modulates sirtuin activity, downstream effects on gene expression, and implications for cellular aging models.
Guarente L. (2013) Cell 155(6):1241-2
Mitochondrial Biogenesis
NAD+-dependent pathways including SIRT1-PGC1α signaling are studied for their role in mitochondrial biogenesis and oxidative phosphorylation regulation. Research investigates how NAD+ supplementation affects mitochondrial density in muscle cell models.
Cantó C. et al. (2012) Cell Metab 15(6):838-47
DNA Repair Research
NAD+ is required for PARP (poly ADP-ribose polymerase) enzyme activity — a key mediator of DNA damage repair. Research examines how NAD+ availability affects PARP-mediated repair efficiency and genome stability in cell culture models.
Canto C. et al. (2015) Cell Metab 22(1):31-53
Why CoreVionRX
Documentation Is the Product.
Most vendors claim purity. We document it. Every compound ships with independent lab verification.
Independent HPLC Testing
Every batch through reversed-phase HPLC before listing. Chromatogram on your COA.
Lot-Specific COA
Your COA tied to your production lot — not a generic template.
Transparent Sourcing
We source and verify. Not a synthesis lab. That honesty builds the brand.
Stability Guaranteed
Lyophilized powder — stable at −20°C for 24+ months.
Common Questions
Straight Answers.
What is NAD+ and is it a peptide?
NAD+ (Nicotinamide Adenine Dinucleotide) is a coenzyme — not a peptide. It is a dinucleotide derived from niacin (Vitamin B3) and is found in all living cells. CoreVionRX carries it as a research compound alongside its peptide catalog because it is frequently studied in longevity and metabolism research.
What research areas use NAD+?
NAD+ research focuses on sirtuin (SIRT1-7) activation, mitochondrial biogenesis via SIRT1-PGC1α pathways, DNA repair through PARP enzymes, and age-related metabolic decline. All research is preclinical or early-stage.
How does NAD+ differ from NMN or NR?
NAD+, NMN (Nicotinamide Mononucleotide), and NR (Nicotinamide Riboside) are related but distinct compounds. NMN and NR are NAD+ precursors — the body converts them to NAD+ intracellularly. Researchers choose between direct NAD+ and precursors based on their specific study design.
How do I dissolve NAD+ for research?
NAD+ is water-soluble and dissolves readily in sterile water, PBS, or appropriate aqueous buffer. No bacteriostatic water needed. Dissolve to your target concentration, filter-sterilize if required by protocol. NAD+ solutions are best used fresh.
How should NAD+ be stored?
Store dry powder at −20°C in a sealed container, away from moisture and light. NAD+ is hygroscopic — moisture accelerates degradation. Keep sealed until use. Solutions should be prepared fresh and not stored long-term.
nad plus research from CoreVionRX is verified at ≥99%% HPLC purity with mass spectrometry confirming the exact peptide sequence.
Every nad plus research vial ships with HPLC verification and a lot-specific COA.
Every vial of nad plus research ships with a lot-specific certificate of analysis so you can verify exactly what is in the vial you received.
CoreVionRX nad plus research is verified by independent third-party testing — mass spectrometry confirms sequence identity and HPLC confirms purity.
Store nad plus research as a lyophilized powder in cool, dark conditions; once reconstituted, keep refrigerated and use within your protocol window.
For accurate reconstitution of nad plus research, use the peptide calculator to calculate the exact water volume needed.
Researchers working with nad plus research should confirm ≥99%% HPLC purity and a lot-specific COA with every order.
For reconstitution, add bacteriostatic water slowly and store nad plus research refrigerated after mixing. Use the peptide calculator to get concentration right.
When sourcing nad plus research, the most important check is purity: every CoreVionRX vial is verified at ≥99% HPLC with a lot-specific COA.
Peer-reviewed research on nad plus research is indexed at PubMed. For research use only.
All CoreVionRX research peptides ship with a lot-specific COA, ≥99%% HPLC purity, and mass-spec identity confirmation. Use our reconstitution calculator for prep. For research use only.
Sourcing verified nad plus research is the first step in any reliable research protocol.
