COA included with every order For laboratory research use only
HPLC Verified≥98% purity confirmed per lot
COA IncludedLot-specific certificate
Mass Spec IDIdentity confirmed per batch
USA OperationsVerified. Documented.
About This Compound
What Is Thymosin Alpha-1?
Thymosin Alpha-1 (TA-1) is a 28-amino-acid peptide naturally secreted by the thymus gland. It was first isolated by Allan Goldstein in 1977 as the active component of Thymosin Fraction 5 — a thymic extract studied for immune modulation. A synthetic version (Thymalfasin) has received pharmaceutical approval in some countries for hepatitis B and C treatment.
In preclinical research, Thymosin Alpha-1 is studied for its effects on T-lymphocyte maturation, dendritic cell activation, NK cell function, and regulatory T-cell modulation. It is one of the most extensively studied thymic peptides in immune system research.
CoreVionRX doesn’t manufacture compounds. We verify every batch rigorously before it reaches our catalog.
≥98%
Purity by HPLC
Reversed-phase HPLC separates and measures compound purity. Documented on your lot-specific COA.
MS/MS
Mass Spec Identity
Molecular weight verified by ESI mass spectrometry — confirms you’re getting exactly what you ordered.
Lot #
Lot-Specific COA
Your COA tied to your production lot. Not standard in this market. We made it standard anyway.
100%
Pre-Listing Verification
No compound ships without full documentation cleared. Non-negotiable policy.
Technical Specifications
Full Product Data
Specification
Value
Compound
Thymosin Alpha-1 (Thymalfasin, TA-1)
Amino Acids
28
Origin
Synthetic analog of thymus-secreted peptide
Form
Lyophilized powder
Vial Size
10mg per vial
Purity
≥98% by reversed-phase HPLC
Identity
Confirmed by electrospray ionization mass spectrometry
Storage (lyophilized)
−20°C, protected from light and moisture. Stable 24+ months.
Reconstitution
Bacteriostatic water or sterile water
Documentation
Lot-specific COA with HPLC chromatogram — included with every order
Preclinical Research
What Researchers Study Thymosin Alpha-1 For
All published research is preclinical — cell cultures and animal models.
T-Cell Modulation Research
Thymosin Alpha-1 is studied for its role in T-lymphocyte maturation and subset differentiation — particularly Th1/Th2 balance and regulatory T-cell (Treg) activity. Research examines how TA-1 modulates T-cell responses in vitro and in immunocompromised animal models.
Goldstein AL. & Garaci E. (2007) Ann N Y Acad Sci 1112:1-7
Dendritic Cell Activation
Preclinical research investigates Thymosin Alpha-1’s effects on dendritic cell maturation and antigen presentation — key to adaptive immune system priming. Studies examine TLR signaling pathway modulation and cytokine production in DC cultures.
Romani L. et al. (2007) Blood 109(2):543-52
NK Cell & Antiviral Research
Research examines Thymosin Alpha-1’s effects on natural killer (NK) cell activity and antiviral immune responses in preclinical models — exploring its potential as an immune adjuvant in combination research protocols.
Tuthill CW. & Rios A. (1994) Int J Immunopharmacol 16(3):181-9
Why CoreVionRX
Documentation Is the Product.
Most vendors claim purity. We document it. Every compound ships with independent lab verification.
Independent HPLC Testing
Every batch through reversed-phase HPLC before listing. Chromatogram on your COA.
Lot-Specific COA
Your COA tied to your production lot — not a generic template.
Transparent Sourcing
We source and verify. Not a synthesis lab. That honesty builds the brand.
Stability Guaranteed
Lyophilized powder — stable at −20°C for 24+ months.
Common Questions
Straight Answers.
What is Thymosin Alpha-1 and where does it come from?
Thymosin Alpha-1 is a 28-amino-acid peptide naturally secreted by the thymus gland. First isolated in 1977 by Allan Goldstein, it was identified as the active component of Thymosin Fraction 5. The research compound is a synthetic version. A pharmaceutical form (Thymalfasin) exists for clinical use in some countries — the research compound is sold separately for preclinical research.
What research areas use Thymosin Alpha-1?
Research focuses on T-lymphocyte maturation, Th1/Th2 balance, regulatory T-cell modulation, dendritic cell activation, NK cell function, and antiviral immune response research. All CoreVionRX compound sales are for preclinical research use only.
How does Thymosin Alpha-1 differ from Thymosin Beta-4 (TB-500)?
Despite similar names, these are completely different peptides with different structures and mechanisms. Thymosin Alpha-1 is a 28-aa thymic peptide studied for immune modulation. Thymosin Beta-4 (TB-500) is a 43-aa actin-binding peptide studied for tissue repair. They belong to different protein families.
How do I reconstitute Thymosin Alpha-1?
Reconstitute with bacteriostatic water or sterile water. Typical research concentrations: 1–5mg/mL. Inject water slowly down the vial wall, swirl gently. Store reconstituted solution at 2–8°C.
How should Thymosin Alpha-1 be stored?
Store lyophilized at −20°C, protected from light and moisture. Stable for 24+ months. After reconstitution, store at 2–8°C. Aliquot before reconstituting to minimize freeze-thaw cycles.
Thymosin Alpha-1 Research Peptide: What to Know Before You Buy
thymosin alpha-1 research peptide from CoreVionRX is verified at ≥99%% HPLC purity with mass spectrometry confirming the exact peptide sequence.
Every thymosin alpha-1 research peptide vial ships with HPLC verification and a lot-specific COA.
Every vial of thymosin alpha-1 research peptide ships with a lot-specific certificate of analysis so you can verify exactly what is in the vial you received.
CoreVionRX thymosin alpha-1 research peptide is verified by independent third-party testing — mass spectrometry confirms sequence identity and HPLC confirms purity.
Store thymosin alpha-1 research peptide as a lyophilized powder in cool, dark conditions; once reconstituted, keep refrigerated and use within your protocol window.
For accurate reconstitution of thymosin alpha-1 research peptide, use the peptide calculator to calculate the exact water volume needed.
Researchers working with thymosin alpha-1 research peptide should confirm ≥99%% HPLC purity and a lot-specific COA with every order.
For reconstitution, add bacteriostatic water slowly and store thymosin alpha-1 research peptide refrigerated after mixing. Use the peptide calculator to get concentration right.
When sourcing thymosin alpha-1 research peptide, the most important check is purity: every CoreVionRX vial is verified at ≥99% HPLC with a lot-specific COA.
Peer-reviewed research on thymosin alpha-1 research peptide is indexed at PubMed. For research use only.
All CoreVionRX research peptides ship with a lot-specific COA, ≥99%% HPLC purity, and mass-spec identity confirmation. Use our reconstitution calculator for prep. For research use only.
Sourcing verified thymosin alpha-1 research peptide is the first step in any reliable research protocol.
