Research Compound · Retatrutide 10mg

Retatrutide Research Compound —
Triple Agonist. Verified.

Retatrutide (GLP-3RT) — investigational triple GIP/GLP-1/glucagon receptor co-agonist. The most comprehensive incretin agonist in preclinical research. 10mg lyophilized, HPLC verified.

≥98% HPLC PurityMass Spec VerifiedLyophilized · 10mgCOA IncludedUSA Operations

Order Retatrutide — $120.00 Read the research guide

$120.00

per 10mg vial

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COA included with every order
For laboratory research use only

HPLC Verified≥98% purity confirmed per lot

COA IncludedLot-specific certificate ships with order

Mass Spec IDMolecular identity confirmed per batch

USA OperationsVerified sourcing. Documented chain.

About This Compound

What Is Retatrutide?

Retatrutide is a synthetic peptide triple agonist targeting GIP, GLP-1, and glucagon receptors simultaneously. Developed by Eli Lilly, it represents the most comprehensive incretin pharmacology in a single compound — adding glucagon receptor agonism to the dual approach of Tirzepatide.

The 10mg format is suited for pilot studies, single-experiment protocols, or researchers beginning their investigation of triple agonist pharmacology before committing to the 30mg format for extended research.

For a full breakdown of the research literature, read our Retatrutide research guide →

// compound profile

CompoundRetatrutide (GLP-3RT)

ClassTriple GIP/GLP-1/glucagon agonist

TargetsGIPR, GLP-1R, GcgR

FormLyophilized powder

Size10mg per vial

Purity≥98% HPLC

What Sets Us Apart

We Verify Before We Ship.

CoreVionRX doesn’t manufacture peptides. What we do — rigorously — is verify every batch before it reaches our catalog.

≥98%

Purity by Reversed-Phase HPLC

HPLC separates the compound from any impurities and measures the exact purity percentage. The chromatogram is documented on your COA.

MS/MS

Mass Spectrometry Identity Check

Electrospray ionization mass spectrometry verifies the molecular weight matches the compound specification. Confirms you’re getting the actual compound.

Lot #

Lot-Specific Certificate of Analysis

Your COA is tied to your specific production lot — not a generic document. This is not standard practice in this market. We made it one anyway.

100%

Documented Before Listing

No compound reaches our catalog without clearing our verification process first. If documentation isn’t available for a batch, that batch doesn’t ship.

Technical Specifications

Full Product Data

Everything you need to evaluate this compound for your research protocol.

Specification	Value
Compound	Retatrutide (GLP-3RT)
Class	Triple receptor co-agonist
Receptor Targets	GIP receptor (GIPR), GLP-1 receptor (GLP-1R), Glucagon receptor (GcgR)
Form	Lyophilized powder
Vial Size	10mg per vial
Purity	≥98% by reversed-phase HPLC
Identity	Confirmed by electrospray ionization mass spectrometry
Storage (lyophilized)	−20°C, protected from light and moisture
Storage (reconstituted)	2–8°C, away from light
Documentation	Lot-specific COA with HPLC chromatogram — included with every order

Preclinical Research

What Researchers Study Retatrutide For

All published research is preclinical — cell cultures and animal models. No human clinical trial data exists for Retatrutide. Here’s where the science currently stands.

Triple Receptor Agonism Research

Retatrutide enables simultaneous investigation of GIP, GLP-1, and glucagon receptor pharmacology — producing research outcomes distinct from dual (Tirzepatide) or single (semaglutide) agonists.

Jastreboff AM. et al. (2023) N Engl J Med 389(6):514-26

Glucagon Pathway Research

Adding glucagon receptor agonism to GIP/GLP-1 activity is Retatrutide’s defining research feature. Research examines glucagon’s role in hepatic glucose production and energy expenditure when co-activated with incretin pathways.

Samms RJ. et al. (2023) Cell Metab 35(9):1517-33

Comparative Incretin Biology

Retatrutide enables comparative research across single, dual, and triple incretin agonist paradigms — providing a comprehensive pharmacological toolkit for metabolic pathway investigation.

Coskun T. et al. (2022) Mol Metab 66:101634

Why CoreVionRX

Documentation Is the Product.

Most peptide vendors claim purity. We document it. Every compound ships with independent lab verification — not because regulations require it, but because you deserve to know exactly what you’re working with.

Independent HPLC Testing

Every batch runs through reversed-phase HPLC before we list it. The chromatogram appears on your COA. Verify the peak profile yourself.

Lot-Specific Documentation

Your COA is tied to your production lot — not a template document. “COA available upon request” is not how we operate.

Transparent About What We Are

We source and verify. We are not a synthesis lab. That honesty is deliberate — it’s the only way to build a brand worth buying from twice.

Lyophilized for Stability

Ships as lyophilized powder — stable at −20°C for 24+ months. Full integrity maintained until you’re ready to reconstitute.

Common Questions

Straight Answers.

What is Retatrutide and how does it differ from Tirzepatide?

Retatrutide activates three receptors: GIP, GLP-1, and glucagon. Tirzepatide activates two (GIP + GLP-1). The glucagon receptor addition in Retatrutide enables research into hepatic glucose production and energy expenditure pathways not accessible with dual agonists alone.

What is the difference between the 10mg and 30mg Retatrutide?

The compound is identical — only the vial size differs. The 10mg format suits pilot studies and smaller-scale experiments; the 30mg format supports extended protocols requiring larger volumes. Both ship with lot-specific COA.

What research areas use Retatrutide?

Research focuses on triple incretin receptor pharmacology, hepatic glucose regulation, energy expenditure, comparative metabolic biology versus Tirzepatide and GLP-1 agonists, and adipose tissue biology.

How do I reconstitute Retatrutide?

Reconstitute with bacteriostatic water. Inject water slowly down the vial wall, swirl gently. Use our reconstitution calculator for exact volumes. Store reconstituted solution at 2–8°C away from light.

How should Retatrutide be stored?

Store lyophilized at −20°C, protected from light. Stable for 24+ months. After reconstitution, store at 2–8°C. Aliquot before reconstituting if your protocol requires multiple preparations to avoid freeze-thaw cycling.

Continue Your Research

Related Resources

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In stock. COA included. HPLC + mass spec verified. Ships with full documentation.

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≥98% HPLC PurityLot-Specific COAMass Spec VerifiedUSA Operations

For laboratory research use only. Not for human or animal consumption.
CoreVionRX supplies research compounds to qualified laboratories and research institutions.

Retatrutide Research Compound —Triple Agonist. Verified.